Zona reticularis is the deepest part of the adrenal cortex. It produces androgen (a steroid sex hormones) in a small quantity. Usually, androgens are produced in the gonads and are supplemented by the androgens produced in the zona reticularis. Adrenal androgens are produced in response to adrenocorticotropic hormone from the anterior pituitary and are converted to testosterone or estrogen. One possible function of andrenal androgens is to help the sex drive in adult female, but it is not well understood in adult men. After menopause when the activity of ovaries decline, androgens from zona reticularis will take place as the main source of estrogens.
OpenStax Physiology. Hormones of the Zona Reticularis. Accessed November 16, 2019. https://openstax.org/